TB-500
Synthetic thymosin beta-4 for tissue repair and inflammation reduction
🛑 WADA Banned 28 views
🛑 WADA BANNED - Prohibited in competitive sports as healing and regeneration peptide
Overview
TB-500 is a synthetic version of Thymosin Beta-4 (Tβ4), one of the most abundant peptides in your body. It's found in nearly every cell and plays a crucial role in how your body heals itself. **What does it do?** TB-500 works by regulating actin, a protein essential for cell movement and structure. When tissue is damaged, TB-500 helps cells migrate to the injury site and promotes the formation of new blood vessels — essentially fast-tracking your body's natural repair process. **What the research shows:** • Promotes healing across multiple tissue types: skin, muscle, tendons, ligaments, heart, and eyes • Reduces inflammation and scar tissue formation • Supports new blood vessel growth (angiogenesis) • May protect heart tissue and improve cardiac function after injury • Widely used in veterinary medicine for racehorses **Common uses:** Athletes and researchers explore TB-500 for injury recovery, particularly for stubborn tendon and ligament issues that heal slowly on their own. **Important to know:** TB-500 is banned by WADA in competitive sports. While animal and veterinary research is extensive, controlled human clinical trials remain limited. --- **Sources:** Goldstein AL, et al. (2022) Current Protein & Peptide Science. DOI:10.2174/1389203724666221201093500 | Xing Y, et al. (2021) Chinese Journal of Burns. DOI:10.3760/cma.j.cn501120-20210221-00059

Quick Facts
Formula:C38H68N10O14
Molecular Weight:4963.00
Sequence:LKKTETQ
Mechanism:Thymosin Beta-4 fragment that enhances cell migration
⚠️ Safety Information
Limited human safety data. Research compound only - not approved for therapeutic use.
Research Citations
Simultaneous quantification of TB-500 and its metabolites in in-vitro experiments and rats by UHPLC-Q-Exactive orbitrap MS/MS and their screening by wound healing activities in-vitro.
Rahaman KA, Muresan AR, Min H, Son J, Han HS, Kang MJ, Kwon OS (2024)
Doping control analysis of TB-500, a synthetic version of an active region of thymosin β₄, in equine urine and plasma by liquid chromatography-mass spectrometry.
Ho EN, Kwok WH, Lau MY, Wong AS, Wan TS, Lam KK, Schiff PJ, Stewart BD (2012)
+ 34 more citations