GLP-1 Weight Loss Calculator
11 medications · 62+ research citations
Medically reviewed: Content based on FDA prescribing information and peer-reviewed clinical trials. Last updated: January 2025
This GLP-1 weight loss calculator helps you estimate your projected weight loss timeline using FDA-approved medications like Wegovy (semaglutide), Mounjaro (tirzepatide), and Saxenda (liraglutide). Enter your current weight, goal weight, height, and activity level to calculate your expected weekly weight loss, total timeline, BMI change, and recommended daily calorie intake. All dosing schedules follow official FDA titration protocols with citations from peer-reviewed research.
Calculate Your Results
Your Results
GLP-1 Medications (11)
Click to selectFDA-Approved
| Medication | Weight Loss | Citations |
|---|---|---|
Wegovy / Ozempic semaglutide | 15-17% | 12 |
Mounjaro / Zepbound tirzepatide | 20-25% | 4 |
Saxenda / Victoza liraglutide | 5-10% | 3 |
Investigational
| Medication | Phase | Weight Loss | Citations |
|---|---|---|---|
| Retatrutide | Phase 2 | 24-27% | 6 |
| Survodutide | Phase 2 | 18-20% | 6 |
| Mazdutide | Phase 3 | 15-18% | 6 |
| CagriSema | Phase 2 | 20-24% | 6 |
| Orforglipron | Phase 2 | 12-15% | 6 |
| Pemvidutide | Phase 2 | 15-18% | 5 |
| Ecnoglutide | Phase 2 | 12-15% | 4 |
| Bioglutide | Phase 1b/2a | 10-12% | 4 |
Wegovy Titration Schedule
View Source →| Phase | Weeks | Dose |
|---|---|---|
| initiation | 1-4 | 0.25 mg |
| escalation | 5-8 | 0.5 mg |
| escalation | 9-12 | 1 mg |
| escalation | 13-16 | 1.7 mg |
| maintenance | 17+ | 2.4 mg |
Citations: Wegovy (12)
- Wegovy (semaglutide) FDA Prescribing InformationFDA Drug Label · 2021
- Once-Weekly Semaglutide in Adults with Overweight or Obesity (STEP 1)New England Journal of Medicine · 2021
Frequently Asked Questions
How much weight can I lose on Wegovy (semaglutide)?
Clinical trials show Wegovy users lose an average of 15-17% of their body weight over 68 weeks. For a 200 lb person, this equates to approximately 30-34 lbs. Results vary based on diet, exercise, and individual metabolism.
What is the Wegovy titration schedule?
Wegovy follows a 16-week titration: 0.25mg for weeks 1-4, 0.5mg for weeks 5-8, 1mg for weeks 9-12, 1.7mg for weeks 13-16, then 2.4mg maintenance dose. This gradual increase minimizes GI side effects.
Is Mounjaro (tirzepatide) more effective than Wegovy?
Yes, clinical data suggests Mounjaro produces greater weight loss (20-25%) compared to Wegovy (15-17%). Mounjaro is a dual GIP/GLP-1 agonist, which may explain its enhanced efficacy for weight loss.
How long does it take to see results with GLP-1 medications?
Most patients notice reduced appetite within 1-2 weeks. Measurable weight loss typically begins by week 4-8. Maximum weight loss is usually achieved between 12-18 months of treatment.
Are GLP-1 medications safe for long-term use?
FDA-approved GLP-1 medications have been studied for long-term safety. Common side effects include nausea, constipation, and injection site reactions. Rare but serious risks include pancreatitis and thyroid tumors. Always consult your healthcare provider.
Do I need a prescription for GLP-1 weight loss medications?
Yes, all GLP-1 receptor agonists for weight loss (Wegovy, Saxenda, Zepbound) require a prescription. They are typically prescribed for adults with BMI ≥30 or BMI ≥27 with weight-related conditions.
GLP-1 medications require a prescription. This calculator provides estimates only and is not medical advice. Consult a healthcare professional before starting any medication.